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Structure |
Catalog # |
Size |
Price
US$ |
In
Stock |
| 2-(Trimethylsilyl)thiazole |
 |
T2744G1 |
1g |
30 |
yes |
| Dondoni Reagent |
T2744G5 |
5g |
120 |
yes |
| Formula: |
C6H11NSSi |
T2744G25 |
25g |
420 |
yes |
| CAS#: |
79265-30-8 |
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| MDL#: |
MFCD00066274 |
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| MW: |
157.31 |
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| Purity: |
98% |
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| InChiKey: |
VJCHUDDPWPQOLH-UHFFFAOYAM |
| InChl: |
1/C6H11NSSi/c1-9(2,3)6-7-4-5-8-6/h4-5H,1-3H3 |
2-(Trimethylsilyl)thiazole (Dondoni Reagent) is used as a stable and convenient substitute for 2-lithiothiazole for introducing various substituents at C-2 of the thiazole ring1. Reactions of Dondoni Reagent with various carbon electrophiles occur readily under mild conditions without the need for any catalyst to give the corresponding 2-substituted thiazoles in fair yields. 1) Dondoni, A.; Fantin, G.; Fogagnolo, M.; Medici, A.; Pedrini, P. J. Org. Chem. 1988, 53, 1748.
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MSDS:
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Download MSDS
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CofA/NMR:
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