| 2-(Trimethylsilyl)thiazole |
| Dondoni Reagent |
| Formula: |
79265-30-8 |
Purity: |
98% |
| MW: |
157.31 |
CAS#: |
C6H11NSSi |
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| Cat# |
| T2744G1 |
| T2744G5 |
| T2744G25 |
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InChI: 1/C6H11NSSi/c1-9(2,3)6-7-4-5-8-6/h4-5H,1-3H3 |
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| 2-(Trimethylsilyl)thiazole (Dondoni Reagent) is used as a stable and convenient substitute for 2-lithiothiazole for introducing various substituents at C-2 of the thiazole ring1. Reactions of Dondoni Reagent with various carbon electrophiles occur readily under mild conditions without the need for any catalyst to give the corresponding 2-substituted thiazoles in fair yields. 1) Dondoni, A.; Fantin, G.; Fogagnolo, M.; Medici, A.; Pedrini, P. J. Org. Chem. 1988, 53, 1748. |
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| ph 919.875.9277 fx 919.875.9601 |
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