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Structure |
Catalog # |
Size |
Price
US$ |
In
Stock |
| 3-Iodooxetane |
 |
I5689G1 |
1g |
180 |
yes |
|
I5689G5 |
5g |
780 |
yes |
| Formula: |
C3H5IO |
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| CAS#: |
26272-85-5 |
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| MDL#: |
MFCD08544403 |
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| MW: |
183.98 |
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| Purity: |
>95% |
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| InChiKey: |
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| InChl: |
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Oxetane ring is a good isosteric replacement for methylene and gem dimethyl motif for improving key physicochemical parameters to assist property guided drug discovery.
Introduction of Oxetane motif at different locations has been shown to
* Improve the physico- and biochemical properties for the active scaffold
* Enhance solubility, reduce lipophilicity, amphiphilicity, and hERG liability
* Impart robust chemical stability under various acidic and basic conditions
* Improve resistance towards metabolic degradation
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MSDS:
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Download MSDS
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CofA/NMR:
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